Indwara ya Mediterranean yumuryango ni iki (FMF)?

Familial Mediterranean Fever ni indwara ya autosomal recessive hereditaire yigaragaza hamwe no kwinubira ububabare bwo munda hamwe numuriro mubitero kandi bishobora kwitiranwa na appendicite ikaze.

Indwara ya FMF ni iki (Familial Mediterranean Fever)?

Indwara ya Mediterane Mediterranean ikunze kugaragara cyane cyane mubihugu bihana imbibi na Mediterane. Birasanzwe muri Turukiya, Afurika yAmajyaruguru, Abanyarumeniya, Abarabu nAbayahudi. Ubusanzwe izwi nka Familial Mediterranean Fever (FMF).

Indwara ya FMF irangwa nububabare bwo munda, kubabara no gukomeretsa mu rubavu (plevitite) no kubabara hamwe no kubyimba (arthritis) bitewe no gutwika igifu, bigaruka mu bitero kandi bishobora kumara iminsi 3-4. Rimwe na rimwe, umutuku wuruhu imbere yamaguru urashobora kandi kongerwaho ishusho. Mubisanzwe, ibi birego birashobora kugenda bonyine mugihe cyiminsi 3-4, nubwo nta muti watanzwe. Ibitero inshuro nyinshi bitera poroteyine yitwa amyloide kwirundanya mumubiri mugihe runaka. Amyloide ikunze kwirundanya mu mpyiko, aho ishobora gutera impyiko zidakira. Ku rugero ruto, irashobora kwirundanyiriza mu rukuta rwimitsi kandi igatera vasculitis.

Ubuvuzi bwa Clinical bubaho biturutse kuri mutation muri gene yitwa pyrin. Yanduza genetiki. Mugihe kuba hariho genes ebyiri zirwaye hamwe bitera indwara, gutwara gene yindwara ntabwo bitera indwara. Aba bantu bitwa "abatwara".

Ni ibihe bimenyetso biranga umuriro wa Mediterane Mediterraneane (FMF)?

Familial Mediterranean Fever (FMF) ni indwara ya genetike ikunze kugaragara mu karere ka Mediterane. Ibimenyetso bya FMF birashobora kugaragara nko gufatwa na febrile, kubabara cyane munda, kubabara ingingo, kubabara mu gatuza, no gucibwamo. Gufata Febrile bitangira gitunguranye kandi mubisanzwe bimara amasaha 12 kugeza 72, mugihe ububabare bwo munda bufite imiterere ityaye, cyane cyane hafi yizuru. Kubabara hamwe byunvikana cyane cyane mubice binini nkivi namaguru, mugihe ububabare bwo mu gatuza bushobora kugaragara kuruhande rwibumoso. Impiswi irashobora kugaragara mugihe cibitero kandi mubisanzwe irashobora kumvikana mugihe gito.

Nigute Indwara Yumuriro Mediterranean Mediterranean (FMF) isuzumwa?

Isuzuma rikorwa hashingiwe kubyavuye mu mavuriro, amateka yumuryango, ibyavuye mu bizamini nibizamini bya laboratoire. Ibi bizamini, hamwe nuburebure bwa leukocyte, kwiyongera kwimitsi, ubutumburuke bwa CRP hamwe nubutumburuke bwa fibrinogen, bifasha mugupima indwara ya Familial Mediterranean Fever. Inyungu zo gupimisha genetike ku barwayi ni nke kuko ihinduka ryagaragaye kugeza ubu rishobora kuboneka gusa muri 80% byabarwayi ba Familial Mediterranean Fever. Nyamara, isesengura rishingiye ku ngirabuzima fatizo rishobora kuba ingirakamaro mu bihe bidasanzwe.

Birashoboka kuvura indwara ya Familial Mediterranean Indwara Yumuriro (FMF)?

Hemejwe ko kuvura colchicine ivura Familial Mediterranean Fever birinda ibitero ndetse niterambere rya amyloidose ku gice kinini cyabarwayi. Nyamara, amyloidose iracyari ikibazo gikomeye kubarwayi batubahiriza imiti cyangwa batinze gutangira colchicine. Kuvura colchicine bigomba kubaho ubuzima bwawe bwose. Birazwi ko kuvura colchicine ari umuti wizewe, ubereye kandi wingenzi kubarwayi bafite umuriro wa Mediterranean familial. Birasabwa gukoresha nubwo umurwayi atwite. Colchicine ntabwo yagaragaye ko igira ingaruka mbi kumwana. Icyakora, birasabwa ko abarwayi batwite bafite umuriro wa Mediterraneane yumuryango bahura na amniocentezi hanyuma bagasuzuma imiterere yimiterere yuruyoya.